Liver diseases associated with SARS-CoV-2 infection: determination of liver serum enzymes in post-COVID-19 patients.
Keywords:
SARS-CoV-2, COVID-19, hepatopatías, enzimas séricas hepáticas.Abstract
The analysis of the Bolivian context during the pandemic caused by the SARS-CoV-2 virus motivated the development of this research, whose objective was to establish the association between liver disease and SARS-CoV-2, through the quantification of liver serum enzymes (AST, ALT, GGT, LDH and ALP); since research worldwide has shown that the aforementioned virus has caused respiratory pathologies and multisystemic pathologies.
The study was observational, descriptive, cross-sectional, non-randomized.The population consisted of 60 people who contracted COVID-19 between December 2020 and March 2021.
The descriptive statistical analysis detected that 65.00% of the participants developed liver disease.The highest elevation was observed in the serum level of GGT with 53.30%. The highest frequency, with 28.33%, corresponds to the mixed enzymatic pattern.
The bivariate statistical analysis between liver disease and COVID-19 severity confirms this association in the “severe” category, followed by the “moderate” category, with RP values >1.00 and p <0.05.
The Quetelet Index (BMI) shows an association with liver disease in the 30– ≥40 category, which corresponds to obese people, with RP values = 1.64 and p <0.05.
In reference to the age variable, the strongest association is observed in the age group between 58–67 years with RP values = 1.68 and p <0.05.
In a manner analogous to international research, the results obtained in this research confirm the association of liver disease with SARS-CoV-2 infection.
